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in the, 2000 BC: Pythagorean triples are first discussed in Babylon and Egypt, and appear on later manuscripts such as the. HMS Department of Neurobiology researchers provide the first molecular explanation for how the blood-brain barrier remains closedby suppressing the process for transporting molecules across cells in vesicles, or small bubbles. Book Three discusses the Linnaean classification system and ends with Darwins theory of evolution by natural selection. . In studies of wound repair, HMS researchers at Boston Childrens find a key molecule, known as PR-39, that binds growth factors and proteins necessary for the mending process. The Scientific Revolution occurs in Europe around this period, greatly accelerating the progress of science and contributing to the rationalization of the natural sciences. Investigating how aspirin reduces inflammation, Brigham and Womens scientists discover that aspirin targets COX, an enzyme involved in the formation of prostaglandins and thromboxanes, compounds that are part of the inflammatory response. From that area, Eannes brought back the first human cargo-two hundred Africans to be sold as slaves in Lagos. Paul Dudley White introduces the electrocardiograph to the United States. Research into the development of insulin has driven scientists to take significant steps towards understanding human biology and a number of Nobel Prizes have been awarded for research into the hormone. 3 Mar. Around this same time, another Spanish explorer, Juan Ponce de Leon, explored Florida and became famous for his quest to find the Fountain of Youth. A printed map gave a reasonably precise portrait of the southward extension of Africa. Concurrently, French physicist, Antoine-Henri Becquerel . In 1787, the French chemist Antoine-Laurent de Lavoisier first discovered the silicon present in rocks. He says the world is made of 4 elements, earth, fire, water and air. ", Columbus and Later Explorations (14921519). It was first published in 1983 and is the first of a trilogy, being followed by The Creators and The Seekers. Created with #1 Rated Timeline Maker Software. A some 15,000 Pilgrims joined The Crusades. He claimed that all the planets, including Earth, moved in orbits around the sun, and showed how this new system could accurately . (2021, February 16). Tombaugh did a careful sky survey at the Lowell Observatory in Arizona. Bernard Lown becomes the first to use direct electric current to restore the rhythm of the heart. 1880 Charles Louis Alphonse Laveran first identifies the malaria parasite. 1958), Learn how and when to remove this template message, The Nine Chapters on the Mathematical Art, Philosophical Transactions of the Royal Society, Universal Natural History and Theory of Heaven, Breakthrough of the Year Breakthrough of the Year, first ever image of a black hole was captured, "In Search of the Earliest Balance Weights, Scales and Weighing Systems from the East Mediterranean, the Near and Middle East", "A Navigational Instrument of the Harappan Sailors", "A Geometric Algorithm with Solutions to Quadratic Equations in a Sumerian Juridical Document from Ur III Umma", "Ancient times table hidden in Chinese bamboo strips", "Quelques textes mathmatiques de la Mission de Suse", "Webpage cites AN INTRODUCTION TO THE HISTORY OF MATHEMATICS", "An Ancient Greek Philosopher Was Exiled for Claiming the Moon Was a Rock, Not a God", "The Adaptation of Babylonian Methods in Greek Numerical Astronomy". A Timeline of North American Exploration: 1492-1585. Parliament passed an act " For providing a Publick Reward for such Person or Persons as shall discover the Longitude at Sea". Sept. 23 Corps of Discovery arrives in St. Louis about noon after two years, four months and 10 days. Clinicians at the Boston Hospital for Women, now part of Brigham and Womens, develop noninvasive fetal heart monitoring, enabling a safer and more accurate way to detect fetal distress during labor. 1600-1050 B.C. In 1811, French chemists Joseph Louis Gay-Lussac and Louis Jacques Thnard probably prepared impure amorphous Silicon by heating potassium with silicon . Discovery of Silicon. This finding may lead to a way to deliver drugs across the barrier and into the brain to treat disorders such as brain cancer, stroke and Alzheimers. It was first published in 1983 and is the first of a . When Eric had been outlawed for manslaughter from his native Norway, he fled to Iceland where he settled at Haukadal in the west. This same gene-finding technique later enables scientists to find genetic markers for other inherited diseases. The best atlases still offered reissues of Ptolemys obsolete maps. The final part of the book, The Infinite and the Infinitesimal, looks at the development of physics, with a particular focus on the atom (the infinitesimal) on one hand and the expansive nature of the universe (the infinite) on the other. In studies to combat the herpes simplex virus type 2, the most common form of genital herpes, David Knipe in HMS Microbiology and Immunobiology develops a replication-deficient vaccine called dl5-29, which stimulates the immune system from inside host cells, a quality other vaccines lack, and becomes a leading candidate in human vaccine trials. During this time, Europeans engaged in unprecedented levels of exploration. 15781580: As part of his circumnavigation of the globe, English sea captain, privateer and traderof enslaved people Francis Drake (15401596) sails around South America and into San Francisco Bay. DNA is found in every cell in the body, and is passed down from parent to child. date the date you are citing the material. The Age of Discovery is sometimes called the Age of Exploration, and the two terms are often used interchangeably. Ed. 12th century AD: Jewish polymath Baruch ben Malka in Iraq formulates a qualitative form of, 1517: Nicolaus Copernicus develops the quantity theory of money and states the earliest known form of. Fuller Albright recognizes the disease of overactive parathyroid, develops an effective treatment for vitamin D-resistant rickets and provides insights into the treatment of osteoporosis. For many years prior, the ground bark had been used to treat malaria. McLean Hospital researchers discover brain proteolipids, a new class of molecules necessary for brain structure and function. 3rd century BC: Archimedes relates problems in geometric series to those in arithmetic series, foreshadowing the. publication in traditional print. Mathematici were expelled not only from Rome and Italy, Ptolemy's " Geography" reached Western Europe, Tycho Brahe writes "Astronomiae Instauratae Mechanica". Research conducted in resource-limited nations by the HMS Department of Social Medicine, now Global Health and Social Medicine, provides the first hard evidence that people infected with multidrug-resistant tuberculosis can be treated successfully by developing community-based outpatient treatment models. When Gil Eannes reported back to Prince Henry that Cape Bojador was impassible, the Prince was not satisfied. Cell Membrane - Robert Hooke in 1665 first view the cells under the microscope and hence, he is credited with the discovery of cell membrane. in History and a M.Ed. Note. Kelly, Martin. McLean researchers identify four types of brain abnormalities associated with abuse and neglect experienced in childhood. Osamu Shimomura, Frank Johnson and Yo Saiga discover green fluorescent protein (GFP) in the jellyfish Aequorea victoria. Spearheaded by faculty in the HMS Department of Global Health and Social Medicine, a report by The Lancet Commission on Global Surgery reveals that 5 billion people are unable to access safe, timely and affordable surgery, leading to 18.6 million preventable deaths each year worldwide. 1521: Portuguese explorer Ferdinand Magellan, funded by Charles V of Spain, sails around South America into the Pacific. In this lesson, we will examine what is commonly called the Age of Discovery. The Prince sent Gil Eannes back with renewed promise of reward for yet another try. The number of major bodies rose to 31 (almost double the 17th century total): Search. The story of North American exploration spans an entire millennium and involves a wide array of European powers and uniquely American characters. They were wrong. Find many great new & used options and get the best deals for Visual Timelines: Science : Inventions and Discoveries Year by Year by Anne Rooney (2023, Hardcover) at the best online prices at eBay! It actually goes back more than 2000 years. The last date is today's A History and Timeline of Autism. Caribbean Islands and America) 1498 CE: Vasco da Gama arrived India: 1503 CE: Leonardo da Vinci started making the painting of Mona Lisa; however . X-ray applications are being used as early as January. He is an adjunct history professor, middle school history teacher, and freelance writer. French explorer Jacques Cartier also explored North America. eNotes.com They found minerals that had to be a sign that even if it wasn't there now, it was at one point. The Discoverers: A History of Man's Search to Know His World and Himself, by Daniel J. Boorstin, is a popular history of human discovery. 1380 AD: The Kerala school develops convergence tests for infinite series. 8 135 B.C. One need not be astonished that the Chinese sages did not make these steps. 1638 - Rene Descartes theorizes that light is a pressure wave through the second of his three types of matter of which the universe is made. 1535: French explorer Jacques Cartier (14911557) explores and maps the Gulf of Saint Lawrence. These findings translate into new treatments that free the immune system to fight tumors. So, I just want to make it easy for you all by jotting down the organelles and their discoverers over here. Nicolaus Copernicus went to much trouble to displace a system that was amply supported by everyday experience, by tradition, and by authority. Mateo Ricci decided to join the Society of Jesuit. 14501500), commissioned by Britain's Henry VII, sights Newfoundland and Labrador, claiming this area for England before sailing south toward Maine and then returning to England. Dana-Farber researchers develop the means to collect, preserve and transfuse platelets to control bleeding. The 20th century produced such a plethora of discoveries and advances that in some ways the face of medicine changed out of all recognition. To unlock this lesson you must be a Study.com Member. Investigators at Boston Childrens isolate and locate on chromosome 21 the gene for the brain protein found in the degenerative nerve tissue of people with Alzheimers disease. 1 . An HMS Genetics team, led by Stephen Elledge, uses a technique called RNA interference (RNAi) to dial down the production of thousands of proteins and determine which are required for cancer cells to survive, exposing a hidden set of drug targets for possible new cancer therapies. van der Waerden, "The Heliocentric System in Greek, Persian and Hindu Astronomy", in David A. 1980 - Klaus von Klitzing discovered the quantum Hall effect. 1898 Sir Ronald Ross demonstrates that mosquitoes transmit malaria. 1974 - Russell Alan Hulse and Joseph Hooton Taylor, Jr. discover indirect evidence for gravitational wave radiation in the Hulse-Taylor binary. 4th century BC: Around the time of Aristotle, a more empirically founded system of anatomy is established, based on animal dissection. I would definitely recommend Study.com to my colleagues. Elliott Joslin becomes one of the first physicians to introduce insulin to the United States and subsequently founds Joslin Diabetes Center. 2003 - After 3bn and 13 years of work, the . "A Timeline of North American Exploration: 14921585." Archimedes invents the screw pump for moving water and other materials. Kelly, Martin. Dana-Farber scientists, led by Bruce Spiegelman, identify a molecular switch in mice that turns on the development of beneficial brown-fat cells, which generate heat and counter obesity. The heliocentric model-Nicolaus Copernicus Nicolaus Copernicus invented the heliocentric model, the heliocentric model, centered around the sun. He claims the area for Queen Elizabeth. Bishop Nicole d'Oresme created the unforgettable metaphor: "a clockwork universe, God the perfect clock maker!". Many of his ideas are wrong but the dominate science for the next 2,000 years. This timeline presents a concise history of the seminal contributions and the scientists who pushed this field forward, from the initial discovery to the first . The Frankish king, Charles the Simple, offered upper Normandy, the area around Rouen, as a fief to Rollo the Ganger, a Viking chief who had brought his invaders twenty years before. Captain Magnus Andersen made a 28-day passage from Bergen to Newfoundland through a stormy sea in an exact replica of the Gkstad ship. In the early 1500s, the continents of the New World, were named 'America,' after his first name. Roland Baron, of Harvard School of Dental Medicine and Mass General, reveals pathways by which the gene. The Strasbourg clock is rebuilt with movable feasts, a Copernican planetarium with revolution of the planets, phases of the moon, eclipses, apparent and sidereal times, procession of the equinoxes, and etc. The Soviet Union aiming to dissolve the Christian year replaced the Gregorian with the Revolutionary calendar. lessons in math, English, science, history, and more. He too searches for the legendary Seven Cities of Gold. A surgical team, led by Ronald Malt, at Mass General performs a replantation of a severed arm, thus achieving the first successful reattachment of a human limb. 1500: Portuguese nobleman and military commanderPedro lvares Cabral (14671620) explores Brazil and claims it for Portugal. HMS Genetics researcher George Church introduces revolutionary "next generation" DNA sequencing technologies. Calvin wrote "Institutes of the Christian Religion". 1584: English writer, poet, soldier, politician, courtier, spy, and explorer Walter Raleigh (15521618) lands on Roanoke Island and calls the land Virginia in honor of Queen Elizabeth. In the summer, he took a full cargo to Iceland intending to follow his usual practice of spending the winter there with his father Heriulf. This website helped me pass! By calculating network scores for the proteins that make up HIV, HMS investigators based at the Ragon Institute of MGH, MIT and Harvard identify specific amino acids in the protein structure of HIV that appear critical to the ability of the virus to function and replicate. Compasses. It seemed that most of Icelands habitable land was fully occupied. Joan Brugge and HMS Cell Biology colleagues discover that cancer cells perish not only via cell suicide, or apoptosis, they can also die of starvation by losing their ability to harvest energy, findings that point toward new tumor-killing strategies. Sahelanthropus tchadensis is one of the oldest known species in the human family tree. Various pieces of modern symbolic notation were introduced in this period, notably: Bhate, S. and Kak, S. (1993) Panini and Computer Science. 1896. In a first, HMS Department of Microbiology scientists use CRISPR-Cas9 gene editing to disrupt both actively replicating and dormant pools of herpes simplex virus in human fibroblast cells, revealing a possible strategy for achieving permanent viral control. Hubble has transformed our understanding of the universe, its view from orbit unleashing a flood of cosmic discoveries that have changed astronomy forever. Battle of Chaeronea | History, Impact & Significance. 6. Beth Israel Deaconess researchers pinpoint the source of preeclampsia, a life-threatening complication of pregnancy and one of the leading causes of maternal and infant mortality worldwide. H. Armstrong Roberts / ClassicStock / Getty Images. This also places Discovery roughly a century after the Captain Jonathan Archer (Scott Bakula)-led Star Trek: Enterprise in the Prime timeline. 15391542: Spanish explorer and conquistador Hernando de Soto (15001542) explores Florida, Georgia, and Alabama, meets the Mississippian chiefdoms there and becomes the first European to cross the Mississippi River, where he is killed by the locals. John Enders, Thomas Weller and Frederick Robbins grow poliovirus in culture, paving the way for polio vaccines. Once explorers realized that the land to the west was a new continent and not part of East Asia, exploration of the New World became a race among the European powers to lay claim to the land. An error occurred trying to load this video. Traditionally, the age of exploration in America begins in 1492 with the first voyage of Christopher Columbus. ~13,000 BCE: Hunters and fishers from Asia that archaeologists call Pre-Clovis entered the Americas from eastern Asia and spend the next 12,000 years exploring the coastlines and colonizing the interiors of North and South America. When Eric was outlawed for manslaughter from his native Norway, he fled to Iceland, where he settled at Haukadal in the west. He was one of the first to realize that the region was, in fact, a new continent and not the Eastern part of Asia. Java was a Dutch colony and at that time Java became one of the main suppliers of coffee. Huygens made a watch with a balance spring. 1936: Seth Neddermeyer, with Carl Anderson, discovered the muon, a negatively charged subatomic particle. However, this is short-lived. For a series ostensibly about exploring the galaxy and meeting new lifeforms in the hopes of sharing knowledge and resources, there sure is a . When compared to other powerful nations such as France, Spain, and the United Kingdom, the history of the United States, which starts in the 17th century, is relatively short. In addition, the Middle East enters the Islamic Golden Age through contact with other civilisations, and China enters a golden period during the Tang and Song dynasties. Other Spanish explorers, like Hernando Cortes and Francisco Pizarro, became known as conquistadors, because they conquered Native American tribes. HMS Microbiology and Immunobiology scientist Arlene Sharpe and Dana-Farber researcher Gordon Freeman show that cancer cells hijack the PD-1 pathway, turning off the immune system. US History Timeline: The Dates of America's Journey. The Age of Discovery came to a close throughout the 1600s as much of the New World became known. Surgeon Joseph Murray performs the first successful kidney transplant on identical twins at Peter Bent Brigham. Massachusetts Eye and Ear clinicians pioneer the use of photodynamic therapy for neovascular macular degeneration. Giovanni de' Dondi completed a clock that combined a planetarium and a timepiece. Working at Boston Childrens, Sidney Farber is responsible for the first successful pediatric remission of acute leukemia. Once the explorers realized they had discovered a new continent, their countries began to explore, conquer, and then create permanent settlements in America. Timeline showing the decade new classes of antibiotic reached the clinic. The timeline begins at the Bronze Age, as it is difficult to give even estimates for the timing of events prior to this, such as of the discovery of counting, natural numbers and arithmetic. 617-432-1000, 2023 by The President and Fellows of Harvard College, Insect-borne disease transmission; scurvy; heat-killed vaccines, Insulin; founding of Joslin Diabetes Center, Overactive thyroid; rickets; osteoporosis, Burn treatment; blood bank; emergency-response plans, Artificial kidney; pediatric remission of acute luekemia, Vaccine culture technique; cortisone; White classification, Platelets; proton beam therapy; implantable cardiac pacemaker, Human limb reattachment; heart rhythm restoration, Human oncogene; positron emission tomography (PET) scan, Artificial skin; premature puberty reversal, Congenital birthmark treatment; Huntington's disease, Kawasaki disease retrovirus; Alzheimer's disease, Early-onset Alzheimer's gene; Duchenne muscular dystrophy gene, Neovascular macular degeneration; microRNAs; paralyzed vocal cord surgical method; colon cancer gene; VEGF molecule, Triple-organ transplant; kidney disease blood glucose levels, How cells sense oxygen; Alzheimer's treatments; immune system advances, Brain abnormalities associated with abuse and neglect, Rheumatoid arthritis pathway; C-reactive protien, Multidrug-resistant tuberculosis treatment; source of preeclampsia, Prenatal nutrition; herpes vaccine candidate, Cholesterol mechanism; DNA sequencing techniques, Cellular switch; rheumatoid arthritis gene; brown-fat cell switch, RIPKI inhibitors; metastatic melanoma remission, LIN28 protien; RNA interference; cancer cells' starvation; brown fat, Kidney failure markers; cancer cell vulnerability; global health care budget models, Tumor suppressor gene p53; ancient migration; infectious disease diagnostics, Cardiac hypertrophy reversal; cathepsin k pathways, Hematopoietic stem cells; pancreatic stem cells, Bioartificial replacement limb; PD-1 pathway; The Lancet Commission on Global Surgery; pseudogene; damaged protein disposal; multiple sclerosis; somatic mutations; deafness gene therapies, Sigma-1 receptor structure; Zika vaccine candidate; circadian rhythm-bipolar disorder link; microbiome, Unlocking the blood-brain barrier; deciphering the structure of a scissorlike enzyme, The 'graying' of T cells; From one cell, a detailed roadmap, Finding herpes' Achilles' heel; viral peptides critical to natural HIV control, Research Departments, Centers, Initiatives and more, Celebrating 50 Years of Diversity and Inclusion, Harvard COVID-19 Information: Keep Harvard Healthy, Learn more about research at HMS on the Quad and beyond, More information about recent discoveries at the Schools 15 affiliates. 1519: Spanish conquistador Hernn Corts (14851547) defeats the Aztecs and conquers Mexico. Archaeologists have found cave paintings, mammoth tusks, and bones marked with lunar phases. The colony collapses within a decade. NASA's real-time portal for Mars exploration, featuring the latest news, images, and discoveries from the Red Planet. Geometry first appeared in the ancient world as a set of rules and formulas suitable for planning, constructing, astronomy, and solving mathematical problems. Pope Gregory ordained that October 4 was to be followed by October 15. Alvise da Cadamosto-a Venetian precursor of the Italian sea captains like Columbus, Vespucci, and the Cabots who served foreign princes-advancing down the coast for Prince Henry had accidentally discovered the Cape Verde Islands and then went up the Senegal and Gambia rivers sixty miles from the sea. Tim Berners-Lee. The Old style calendar was changed to the New Style calendar. However, it's best to recognize that Columbus wasn't the first human to put a foot in the Americas. Philip Drinker invents the iron lung to help polio-paralyzed patients breathe. 1800 BC 1600 BC: A numerical approximation for the square root of two, accurate to 6 decimal places, is recorded on, 19th to 17th century BCE: A Babylonian tablet uses, 3000 BC: The first deciphered numeral system is that of the, 2000 BC: Primitive positional notation for numerals is seen in the, Early 2nd millennium BC: The periodicity of planetary phenomenon, Early 2nd millennium BC: Ancient Egyptians study anatomy, as recorded in the, 4th century BC: Greek philosophers study the properties of logical, 4th century BC: The first true formal system is constructed by, 4th-3rd century BC: In Mauryan India, The Jain mathematical text. Age of Exploration- By Ashley Vu, Brian Le, Danny Trinh, and Veursace Thorton, The Age of Exploration 1500-1800 Jose Benavidez, Tommy Nguyen, Jeffry Norales, Age of Exploration Timeline by Kezia Ng, Masoud Said, and Nuhan Azad, Age of Exploration Timeline (1500s-1800s) by Anita Igben, Jennifer Dao, and Julie Vo. 1590 - Janssen & Lipperhey work on Compound Lenses. The Age of Discovery was a period of time between the 1400s and 1600s. Other theoretical and experimental advances of the 1970s confirmed this discovery, leading to the present standard model of elementary particle physics. Ten sample tubes, capturing an amazing variety of Martian geology, have been . In 1497, John Cabot landed somewhere in Northern North America (probably near Newfoundland) and claimed the region for England. Dolly is the first mammal cloned from a non-embryonic cell. Dana-Farber scientists identify the gene that causes an inherited form of colon cancer, which leads to diagnostic screening to determine whether people are predisposed to contract the disease. All rights reserved. From Prince Henrys household went Nuno Tristo and Anto Gonalves, reaching another two hundred fifty miles farther to Cape Branco (Blanco) where they took two natives captive. By prescribing the antibiotic actinomycin D in addition to surgery and radiation therapy, they boost cure rates from 40 to 85 percent. Spanish explorer Vicente Yez Pinzn (1462ca. The Japanese changed from the "natural" sunlight day divided into six equal hours between sunrise and sunset. 350-50 BC: Clay tablets from (possibly Hellenistic-era) Babylon describe the mean speed theorem. the sum of consecutive integers), by the Pythagoreans. Carl Walter, John Merrill and George Thorn perfect the Kolff-Brigham artificial kidney for clinical use. 1514) and the (possibly) Portuguese explorer Juan Daz de Sols (14701516) sail into the Gulf of Mexico and visit the Yucatan peninsula and the coast of Florida. While treating victims of the Cocoanut Grove fire in Boston, Massachusetts General Hospital physicians demonstrate the efficacy of a new approach to burn treatment and the value of new blood bank and emergency-response plans. Man has long coped with uncertainty and the change brought on by nature's . Benjamin Waterhouse introduces the smallpox vaccine to the United States and helps gain acceptance for the new procedure. 1729 - Chester Moore Hall invents Achromatic Lens. Walking upright may have helped this species survive in diverse habitats, including forests and grasslands. 4. By the 5th century AD: The elliptical orbits of planets are discovered in India by at least the time of Aryabhata, and are used for the calculations of orbital periods and eclipse timings. This helped the world in that scientists could make new discoveries about oceans ans sea-life. Pope Gregory XIII took ten days out of the calendar. 79-94. 384-322 BC Aristotle lives. The " Chinese Caesar" , King Cheng, managed within 25 years to unify a half-dozen Chinese provinces into a single great empire, with a vast hierarchy of bureaucrats. The life of the Chinese pioneer Chang Heng. The second is the date of Centriole - Discovered by Edouard Van Beneden in 1883 and was described and coined by Theodor . Then they took the rover to Mars' north pole and found what appeared to be a powdery white color. 1473: Portuguese sailor Joo Vaz Corte-Real (14201496) explores (perhaps) the coast of North America, a land he calls Terra Nova do Bacalhau(New Land of the Codfish). CBS News reported on Monday that on Nov. 2, roughly 10 documents were discovered at a . There is a section on anatomy and medicine, with particular focus on the work of Edward Tyson. James Gusella leads the HMS Genetics team that finds a genetic marker for Huntingtons disease, a fatal inherited condition. c. 60 AD: Heron's formula is discovered by, 4th to 5th centuries: The modern fundamental trigonometric functions, sine and cosine, are described in the, By the 4th century AD: a square root finding algorithm with quartic convergence, known as the, 1st to 4th century AD: A precursor to long division, known as ". Skip Navigation. Robert Hooke. Age of Explorations 1500-1800. 2023 . Peter Park, in the HMS Department of Biomedical Informatics, leads a study demonstrating for the first time that a large number of somatic (noninherited) mutations are present in the brain cells of healthy people and occur more frequently in the genes that neurons use most. 1400: Descendants of Easter Islanders land on the Chilean coast of South America and hobnob with the local residents, bringing chickens for dinner. Johannes Kepler discovered that earth orbited the sun and could also prove it. 1630 - Vincenzo Cascariolo, a Bolognese shoemaker, discovers fluorescence. Passing through the jungles of Panama in 1513, he became the first European to reach the Pacific Ocean by way of the Atlantic. Virologists at Beth Israel Deaconess find two candidate vaccines that provide complete protection from the Zika virus in animal models, suggesting a vaccine for humans may be feasible. "Hipparchus' Treatment of Early Greek Astronomy: The Case of Eudoxus and the Length of Daytime Author(s)". Dana-Farber scientists achieve a medical first by using a targeted drug to drive a patient's metastatic melanoma into remission. Christopher Columbus' discovery of the New World in 1492 was undoubtedly the pivotal event of the Age of Discovery. X-rays are discovered by Wilhelm Conrad Roentgen in 1895, Germany. c. 300 BC: Euclid proves the infinitude of primes. 1952 Discovery: Genes Are Made of DNA Search in. Book 1: TIME 00000 % complete "Time is the greatest innovator" - Francis Bacon(1625) Part 1:The Heavenly Empire The Temptations of the Moon Note. As a result, he discovered Pluto. 1675 - More than 3000 coffeehouses in England.